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Research Publications

Stories about recent journal articles featuring work by MCB faculty and students.

Light targets cells for death and triggers immune response with laser precision

A new method of precisely targeting troublesome cells for death using light could unlock new understanding of and treatments for cancer and inflammatory diseases, University of Illinois Urbana-Champaign researchers report...

When an orange behaves like an apple: New research pinpoints rules governing reaction outcomes of G-protein-modifying toxins

A group of researchers from the University of Illinois has identified a set of rules governing the reaction preferences of a family of G-protein-modifying toxins. G proteins are proteins that regulate cellular processes through interactions between hormone receptors and downstream signaling...

From 'CyberSlug' to 'CyberOctopus': New AI explores, remembers, seeks novelty, overcomes obstacles

By giving artificial intelligence simple associative learning rules based on the brain circuits that allow a sea slug to forage — and augmenting it with better episodic memory, like that of an octopus — scientists have built an AI that can navigate new environments, seek rewards, map landmarks and...

New antibiotic kills pathogenic bacteria, spares healthy gut microbes

Researchers have developed a new antibiotic that reduced or eliminated drug-resistant bacterial infections in mouse models of acute pneumonia and sepsis while sparing healthy microbes in the mouse gut. The drug, called lolamicin, also warded off secondary infections with Clostridioides...

New study highlights need for cell-type-specific therapies in treatment of HIV

Researchers from the University of Illinois have demonstrated the importance of cell-type-specific targeting in the treatment of HIV. Their findings, published in PNAS, are one of the first to examine the differential or cell-type...

Researchers decode movement pattern of landmark polar protein

A trio of researchers from the Department of Microbiology has discovered an essential function of a landmark protein in regulating movement across bacterial cells. Members of the Mera Lab determined how the coiled-coil polar protein TipN moves a region of the chromosome called parS. They also...

Researchers identify key regulators underlying regeneration in Drosophila

Some animals possess the remarkable ability to regenerate lost structures, exemplified by a lizard regrowing its tail. However, this regenerative process must be tightly regulated by the body to ensure proper tissue organization and to prevent abnormal growths, such as cancer. Yet, the precise...

New study uncovers novel receptor function in Fragile X syndrome

Fragile X syndrome is one of the most commonly inherited forms of autism and intellectual disability, and no treatment currently exists. But a team of University of Illinois researchers led by Vipendra Kumar, a postdoctoral researcher in the Department of Molecular & Integrative Physiology, has...

Mice study suggests metabolic diseases may be driven by gut microbiome, loss of ovarian hormones

The gut microbiome interacts with the loss of female sex hormones to exacerbate metabolic disease, including weight gain, fat in the liver and the expression of genes linked with inflammation, researchers found in a new rodent study. The findings, published in the journal...

Unveiling the Role of SNUL RNAs in Ribosomal RNA Expression Regulation

A new study by University of Illinois scientist Dr. Kannanganattu V. Prasanth and his team of researchers at Illinois and across multiple institutions has shed light on a novel family of noncoding RNAs (ncRNAs), and their significant...